Cardinal Pietro Parolin attends an ordination at the Basilica of Sant’Eugenio in Rome, Sept. 5, 2020. / Daniel Ibáñez/CNA.

Vatican City, Jan 18, 2022 / 07:05 am (CNA).

Cardinal Pietro Parolin and Archbishop Edgar Peña Parra have tested positive for COVID-19, the Holy See press office confirmed on Tuesday.

Parolin, the Vatican Secretary of State, has “very mild” symptoms, while his Venezuelan substitute, Peña Parra, is asymptomatic, Vatican spokesman Matteo Bruni told journalists on Jan. 18.

Archbishop Edgar Peña Parra meets with Pope Francis in Vatican City on August 17, 2018. . Vatican Media

Both members of the Roman Curia were fully vaccinated and had received booster shots.

Earlier this week, Parolin, who travels frequently for his diplomatic role, canceled a trip to Erba in northern Italy scheduled for Feb 6. The cardinal turned 67 on Jan. 17.

Parolin issued further coronavirus restrictions within Vatican City last month, requiring people to provide either proof of vaccination against COVID-19 or evidence of recovery from it to enter Vatican offices.

Many cardinals have tested positive for COVID-19 since the outbreak of the pandemic in 2020, including Cardinal Luis Antonio Tagle, Cardinal Konrad Krajewski, Cardinal Wilton Gregory, Cardinal De Donatis, and Cardinal Raymond Burke.